On January 26, 2018 the Department of Psychological and Brain Sciences welcomed Dr. Sheena Josselyn as this year’s Leaton Lecturer in Behavioral Neuroscience. Dr. Josselyn presented a tour-de-force colloquium entitled “Making Memories,” that brought to bear state of the art neurogenetic, optogenetic, and calcium imaging techniques to answer age-old questions regarding the biological mechanisms supporting the ‘engram,’ or the representation of a memory in the brain. Dr. Josselyn is a Professor in the departments of Psychology, Physiology and the Institute of Medical Sciences at the University of Toronto and is a Canada Research Chair in Brain Circuits and Memory. Dr. Josselyn is also a Senior Fellow of the Canadian Institute for Advanced Studies. In addition to field-leading research, she is also passionate about high quality mentoring of young scientists and graduate education, a topic she also addressed during her visit. Dr. Josselyn was the eleventh Leaton Lecturer, an colloquium dedicated each year to Professor Emeritus Robert Leaton.